A method for arrayed CRISPRi screening in organoids enables the investigation of morphogenesis in human stem cell-derived tissues, revealing the roles of ZIC2, SOX11, and ZNF521 in neural tube closure ...

Researchers have developed a new tool that can screen genes involved in human development at unprecedented scale and speed, using it in a proof-of-principle study to reveal new insights into human ...

UCSF researchers are using tiny "mini-organs" to model disease, personalize treatment, and understand human development. They ...

Scientists have developed a promising new approach to treating Alzheimer’s disease by turning ordinary brain cells into powerful plaque-clearing machines. Instead of requiring frequent antibody ...

Researchers at the Icahn School of Medicine at Mount Sinai and the Lieber Institute for Brain Development have identified ...

A new study constructs the first 3D single-cell brain atlas of the lamprey, uncovering the 450-million-year-old molecular ...

A new study of bilingual speakers suggests that a single “grammatical engine” in the brain can power multiple languages at once. By K. R. Callaway Speak a language your whole life and its grammatical ...

Creative Biolabs, a leader in single-cell resolution solutions, has announced the strategic enhancement of its ...

Osteoporosis (OP) and cognitive decline are highly prevalent comorbidities; however, the molecular mechanisms linking them remain unclear. We adopted a multimodal integrative strategy combining ...

Brain cells that help make us human are also uniquely vulnerable to multiple sclerosis. A newfound cellular repair kit can’t keep up with the disease’s damage, leading to the cell death that’s a ...

Researchers observed the psychological effects after participants took a 25 mg dose. Single psilocybin dose altered brain structure and improved well-being in healthy adults. Brain scans showed denser ...