Metabolic reprogramming is the hallmark of malignant tumors. Both metabolic phenotype and metabolic dependence are changed during the development of cancer from precancerous tissue to local invasion ...

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Plus: SpaceX has officially delivered the largest IPO in history. This is today's edition of The Download, our weekday newsletter that provides a daily dose of what's going on in the world of ...

Background SIRT6 acts as a tumour suppressor in multiple cancers by regulating glucose and lipid metabolism, but its role in intrahepatic cholangiocarcinoma (ICC) remains unclear. Objective We ...

Test time has arrived: the first person has been treated in a highly anticipated gene-therapy trial that aims to coax aged cells to take on a younger identity. The clinical trial is testing an ...

The next step in the youth quest is a technology called chemical reprogramming. The outspoken longevity scientist David Sinclair has been predicting that one day, you’ll go to the doctor and get a ...