Background Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction, with some recommended treatments targeting brain-gut axis dysfunction. Objective To compare relative efficacy of ...
I read the GOULASH trial with great interest. This multicentre, double-blind randomised clinical trial compared early high-energy enteral nutrition (30 kcal/kg/day) with a gradually increasing energy ...
Bacterial infection is a frequent trigger of acute-on-chronic liver failure (ACLF), syndrome that could also increase the risk of infection. This investigation evaluated prevalence and characteristics ...
The study by Pandanaboyana et al 1 showed that acute pancreatitis (AP) patients with COVID-19 had a significantly higher mortality than those without COVID-19. Nevertheless, a similar trend of ...
Correspondence to Dr Gyongyi Szabo, Department of Medicine, Division of Gastroenterology, Beth Israel Deaconess Medical Center, Boston, MA 02115, USA; gszabo1{at}bidmc.harvard.edu Objective Alcohol ...
Correspondence to Dr Manon C W Spaander, Department of Gastroenterology and Hepatology, Erasmus MC University Medical Center, Rotterdam 3015 CE, The Netherlands; v.spaander{at}erasmusmc.nl Objective ...
Background Sympathetic signalling plays a critical role in the initiation and progression of various malignancies. However, its specific contribution to intrahepatic cholangiocarcinoma (iCCA) remains ...
Background and aims: Crohn’s disease (CD) and ulcerative colitis (UC) are chronic multifactorial inflammatory bowel diseases (IBDs) with unknown aetiology, but a deregulated mucosal immune response to ...
Prof. Dr C H C M Buys, Department of Medical Genetics, University of Groningen, A. Deusinglaan 4, NL-9713 AW Groningen, The Netherlands. Background—Germline mutations of the RET proto-oncogene ...
Background Acute appendicitis is a local intestinal inflammation with unclear origin. The aim was to test whether bacteria in appendicitis differ in composition to bacteria found in caecal biopsies ...
Background and aim Disease activity for Crohn's disease (CD) and UC is typically defined based on symptoms at a moment in time, and ignores the long-term burden of disease. The aims of this study were ...
1 National Centre for Bowel Research and Surgical Innovation and GI Physiology Unit, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK Objective The ...