RNA has emerged as one of the most promising molecules in modern medicine, enabling advances from mRNA vaccines and gene ...

The phosphorylation of proteins in eukaryotic cells is a key post-translational modification that regulates essential and diverse biological phenomena. Phosphorylation is installed by protein kinases ...

A molecule called tRNA is an essential component of the human genome that acts as a translator. When researchers and clinicians investigate the genome's relation to disease, they have traditionally ...

Documenting the first substantial thing I did in my own lab at CU, discovery of the ability of Aminoacyl RNA Synthetases (AARS) to correct aminoacylation mistakes (simultaneous with Eldred & Schimmel, ...

Prostate cancer is the second-most common cancer in men. A new study from Thomas Jefferson University uncovered a new potential therapeutic target in tiny molecules called tRNA halves. "Because tRNA ...

A groundbreaking study has shed light on the critical role of a tRNA methylation enzyme, TRMT10A, in supporting brain function. The findings reveal how the absence of TRMT10A leads to a reduction in ...

Overview of RNA repair – There is an emerging appreciation of the existence of “RNA repair” pathways that rely on RNA ligases to maintain or manipulate RNA structure in response to purposeful RNA ...

Peking University, June 27, 2025: To overcome the inherent challenge of translation termination interference caused by stop codon reprogramming in mammalian cells, researchers from Peking University ...