Oocyte maturation and follicular development are fundamental processes that underpin female fertility. These processes involve the transformation of primordial follicles into a cohort of mature, ...

The presence of an organelle called the fusome in species as diverse as Drosophila and mammals indicates an ancient, conserved programme of germ cell development.

Researchers have found that a carefully orchestrated act of X-chromosome 'yoyo' predicts the successful and efficient development of mammalian egg cells. The findings could pave the way for generating ...

When the female germline develops, oocyte growth is accompanied by many changes in gene expression, however, the regulatory networks that control this process have not been determined. Now, a group of ...

An ovary is only a few centimeters wide, but its precious cargo is even smaller. Oocytes are a few dozen micrometers in diameter and are individually wrapped in layers of specialized cells that form a ...

The new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for ...

The many types of cells in the human body are produced through the process of differentiation, in which stem cells are converted to more specialized types. Currently, it is challenging for researchers ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...