One of the most enduring goals in regenerative medicine is deceptively simple: replace a person's damaged or dying cells with ...

One of the holy grails of biology is digitally simulating a living cell. If researchers can use computers to more accurately understand how new medicines would react in the body, that could give them ...

Over the last 15 years, I have witnessed how cell and gene therapy (CGT) has evolved in many ways, spanning from research and development to manufacturing. Breakthroughs such as CAR-T and gene therapy ...

The development of humans and other animals unfolds gradually over time, with cells taking on specific roles and functions ...

The International Society for Stem Cell Research (ISSCR) Embryo Models Working Group has released updated recommendations for the oversight and regulation of stem cell-based embryo models (SCBEM), ...

Drug discovery requires experimental systems that more accurately capture the complexity of human tissues. However, animal models and conventional cell culture approaches often lack the physiological ...

Creating human structures in a lab is always difficult, but when successful, it can open up a lot of possibilities. Recently, researchers have been working on using 3D embryo structures called ...

Our body’s “blood factory” consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types. Now, researchers have succeeded for the first time in recreating this ...

Researchers from the Keck School of Medicine of USC have developed a new type of chimeric antigen receptor (CAR) T cell that elicits a more controlled immune response to cancer in mice—effectively ...