Lipid-binding sites and properties were compared in the hetero-oligomeric cytochrome (cyt) b₆f and the yeast bc₁ complexes that function, respectively, in photosynthetic and respiratory electron ...
The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.
Lipid kinases are among the promising targets of new classes of drugs, due mainly to class I PI3Kα, which plays a crucial role in carcinogenesis and metastasis. This enzyme is hyperactive in 30-40% of ...
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Lipid nanoparticle structure shapes cell uptake: Cubosomes fuse with membranes for efficient delivery
Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big impact on how well our cells absorb them, paving the way to more efficient ...
This project explores how a specific group of lipids, key membrane components and dynamic signaling molecules, shape cellular fate by regulating both senescence and cell death. Project is Not ...
This study mapped how EPA and DHA are distributed across lipid classes in microalgae, fish, krill, and commercial omega-3 ...
To create A1 lipid nanoparticles for delivering mRNA to target cells, scientists at the University of Pennsylvania used A3 coupling. A3 refers to the amine–aldehyde–alkyne coupling reaction, which the ...
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