A study from FAU has shown that lipid nanoparticles restructure their membrane significantly after being absorbed into a cell and ending up in an acidic environment. Vaccines and other medicines are ...

A new study shows that lipid nanoparticles restructure their membrane significantly after being absorbed into a cell and ...

LNPs are solid or semi-solid particles at room temperature. They are composed of a lipid core stabilized by surfactants or other agents. This lipid core provides a hydrophobic environment ideal for ...

Crenarchaeol is a large, closed-loop lipid that is present in the membranes of ammonium-oxidizing archaea. In comparison to other archaeal membrane lipids, crenarchaeol is very complex and, so far, ...

Aircraft wing-shaped structures inside tiny channels produce consistent drug delivery particles at any scale, from small laboratory tests to factory production, while substantially cutting costs.

Dustin Dovala, Christopher M. Rath, Qijun Hu, William S. Sawyer, Steven Shia, Robert A. Elling, Mark S. Knapp, Louis E. Metzger IV Proceedings of the National Academy ...

The cytokine-producing signal protein, a target for drug hunters, has additional activators that could be manipulated ...

This new article publication from Acta Pharmaceutica Sinica B, discusses how structure-guided design of picomolar-level macrocyclic TRPC5 channel inhibitors with antidepressant activity.

Scientists who work with lipid nanoparticles (LNPs) say they have developed a new type of material capable of reaching the lungs and the eyes. They call their study “Thiophene-based lipids for mRNA ...