More than 15 years ago, Yale's Gail D'Onofrio started studying the effectiveness of sublingual (under-the-tongue) buprenorphine for treatment of opioid use disorder (OUD) in the emergency department.

You can inject Mounjaro subcutaneously (under the skin) at three sites: your abdomen, thigh, or upper arm. But be sure to change sites weekly and follow all instructions to inject Mounjaro correctly.