DNA transcription is a crucial process in the expression of genetic information, as it converts the information stored in DNA into messenger RNA, which can then be translated into proteins. Without ...

Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing RNA in eukaryotic cells and eventually giving rise to proteins. Scientists ...

RNA Polymerase (shown in blue) moves across a template strand of DNA (shown in purple) and transcribes it into RNA (shown in red). But DNA damage blocks the RNA polymerase, causing it to stall and ...

A cell protein previously believed only to provide a scaffolding for DNA has also been shown to directly influence DNA transcription into RNA – the first step of the process by which an organism's ...

A massively parallel reporter assay of 9,092 cortical-structure-associated variants reveals that Alu retrotransposons, Wnt ...

Researchers have discovered that in thale cresses histone H3 lysine-9 (H3K9) methylation, conventionally thought to be a mark of turning off gene transcription, can also turn on gene expression via ...

The ATR–ATRIP kinase complex safeguards genome integrity by coordinating cellular responses to DNA damage and replication stress. Two recent cryo-EM studies resolve the structural basis of ATR–ATRIP ...

Researchers have shown that RNA droplets trap their own DNA templates, and that even low rates of mutation produce stable ...

Life starts with one cell. When an organism develops, dividing cells specialize to form the variety of tissues and organs that build up the adult body, while keeping the same genetic ...

An essential cellular enzyme successfully transcribed synthetic DNA letters, bringing expanded genetic codes closer to biological use.

A vertical, purple double helix has a bumpy, light-blue shape attached at the bottom and a blue cross made of many strands at the top. One end of the cross is bright pink and has dots around it, and a ...