Every time a cell divides, it must copy its DNA with extraordinary precision. But this process is constantly challenged by DNA damage. Among the most dangerous lesions are DNA interstrand crosslinks ...

Embryonic stem (ES) cells are pluripotent stem cells that can produce all cell types of an organism. ES cells proliferate rapidly and have been thought to experience high levels of intrinsic ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...

Cells have evolved careful checks to ensure DNA is copied only once, but how they switch on replication at the right moment ...

So-called junk DNA was given that unfortunate nickname because its function was so mysterious. These vast regions of the genome do not code for protein and are made up of highly repetitive sequences.