If severe DNA damage is not repaired, the consequences for the health of cells and tissues are dramatic. A study led by ...

“By enhancing DNA repair, we can heal tissue damage that occurs during a heart attack,” Ibrahim said. “We are particularly excited because TY1 also works in other conditions, including autoimmune ...

Particle therapy, including proton and carbon ion radiotherapy, represents a major advancement in cancer treatment due to its ...

New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...

Unrepaired DNA-protein crosslinks (DPCs) – highly toxic tangles of protein and DNA – cause a process that leads to premature ...

Once failed in high school chemistry due to a teacher’s judgement, Tomas Lindahl later reshaped the same discipline. Awarded the 2015 Nobel Prize in Chemistry for his pioneering DNA repair research, ...

In a quiet lab at Utrecht University, researchers have built a tool that lets you watch one of life’s most serious crises unfold in real time. Inside every cell, DNA breaks, repairs, and sometimes ...

DNA is often described as the instruction manual for building the fundamental components of life. Proteins are helpers that ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among the most dangerous forms of DNA damage and immediately trigger the cell's ...

DNA can be damaged by normal cellular processes as well as external factors such as UV radiation and chemicals. Such damage can lead to breaks in the DNA strand. If DNA damage is not properly repaired ...