Single-molecule chromatin tracing in C. elegans embryos has revealed three distinct classes of megabase-scale heterochromatin domains, including condensin-dependent TAD-like structures and ...

An unexpected lab observation has led a team of scientists to discover how diet can influence survival in animal models of glioma, one of the most aggressive and deadly forms of brain cancer.

Certain epigenetic modifications can directly control how genetic material is packed in the nucleus, RIKEN researchers have shown. This has important implications for our understanding of how genes ...

For decades, biology textbooks have drawn a deceptively simple picture of the genome’s physical state: dark, tightly packed ...

Inside each human cell, about 2 meters (6.6 feet) of genomic DNA must be accurately copied and equally transmitted to two daughter cells during cell division. To achieve this, the copied DNA is ...

A novel, freely available AI tool has cut the time it takes to determine chromatin structure from days to minutes. The 3D structure of DNA is important for controlling cell-specific gene expression ...

A study on dogs found that chromatin's spatial structure has a significant role in the evolution of social behavior. Chromatin, the compact form of DNA, not only packages genetic material but also ...

Every cell in your body has spent its entire existence under gravity’s pull. Inside each of them, roughly two meters of DNA ...

This study is led by Dr. Yue Zhou (State Key Laboratory of Gene Function and Modulation Research, School of Advanced Agricultural Sciences, Peking-Tsinghua Center for Life Sciences, Peking University, ...

The effects of disease-associated genetic variants on gene expression and genome accessibility have been analysed together.

A study described the three-dimensional architecture of turtle genomes, which fold in a configuration unlike any other animal observed so far. In their long strings of nucleotides, DNA molecules hold ...