A study published in Cell Research advances a central idea in stem cell biology by identifying a checkpoint that controls the identity of many different types of stem cells across developmental stages ...

Natural killer (NK) cells are pivotal in the innate immune response against cancer and viral infections, with their presence in tumors correlating to better patient outcomes in various cancers.

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...

Cell division is an essential process for all life on Earth, yet the exact mechanisms by which cells divide during early embryonic development have remained elusive—particularly for egg-laying species ...

A review discussing the therapeutic potentials of NK cell biology has been published in the journal Frontiers of Medicine. This exhaustion is influenced by immune checkpoint receptors, which are ...

Scientists from USC and the NIH have identified the protein GSK3α as a universal 'stemness checkpoint' that regulates stem cell differentiation across species. Inhibiting GSK3α allowed multiple stem ...

If you took high school biology, you probably learned about cell division: a crucial process in all life forms officially called mitosis. For over one hundred years, students have learned that during ...

Checkpoint inhibitors are antibody-based cancer therapies that unlock the immune system’s natural ability to fight cancer. These treatments work by blocking special proteins called immune checkpoints, ...

In a new paper published in Cancer Research, researchers at MUSC Hollings Cancer Center have shown that targeting a protein called TACC3 (transforming acidic coiled-coil containing protein 3) can ...